NC Tweener Fund

LifeFlow rapid fluid infusion devices

Automated digital advertising for real estate and financial services

Turns non-standardized aircraft maintenance records into structured data for aviation reliability and uptime analysis.

Developer analytics for project health visibility

Intestinal tissue models for drug development

AI data-engineering agents that build, debug, and maintain data pipelines

Marketplace platform for contact-center and customer-experience outsourcing

Cloud disaster recovery platform.

Cultivated seafood through cellular agriculture

AI-driven climate-resilient crop development using machine learning

Public-safety startup building an AI platform that reduces the administrative work police officers spend on, bringing a department's records management, email, policy and personnel, and communications systems under one interface so desk-side tasks (paperwork, compliance, investigations, event planning) take less time.

Professional network and referral community for mental health professionals.

Food-as-medicine health coaching platform for gut health, weight, and diabetes

AI vision systems and robotics for warehouse and hospital automation.

AI/robotics for automated home building panels

AI-assisted home-design and DIY visualization app. Helps homeowners and upcyclers plan, visualize, and share interior-design, furniture, and upcycling projects through an easy-to-use mobile interface.

Operations management software for real-time workflows, automated tasks, and connected teams.

AI-powered phone answering for social services. Answers resident calls in English and Spanish 24/7 for cities, counties, 311/211, public health agencies, community health centers, community action agencies, and shelter services, with handoff to live staff for urgent cases.

AI automation platform for industrial operations. Encodes expert decision-making for make-ready engineering, permitting, and joint-use workflows across utilities, telecom, engineering firms, and agribusinesses.

Composting service for individuals and businesses

Youth sports management app for clubs, events, recruiting, and payments.

WMS testing platform for enterprise warehouse management systems.

AI visual infrastructure for ecommerce brands.

Airport virtual dining hall and multi-brand concessions operator

AI-powered financial operations platform for startup bookkeeping and cap table management.

Advanced tests for flea/tick-borne diseases

AI-powered squad planning and roster-management platform for sports teams.

Medical imaging data platform for training and validating AI models

Sustainability reporting and ESG compliance software for suppliers.

Climate and sustainability technology

AI-powered equipment procurement platform for independent practices.

AI-powered revenue enablement platform

AI recruiting assistants for staffing teams, covering candidate screening, scheduling, enrichment, and matching.

AI-powered quality measurement system (QMS) for medical devices -- like having a regulatory expert 24/7

Homebuilding AI platform for design, estimating, sales, and construction workflows.

Technology-enabled general contractor for home evaluations, repairs, and home management.

Understandable AI software platform, formerly Diveplane.

Fintech platform that scores consumer spending for social and environmental impact and connects it to rewards and card products.

AI observability and reliability platform for enterprise IT operations and AI workloads.

Movement-intelligence platform that uses wearable data to help athletes detect injury risk and adjust training.

AI-first risk adjustment platform for healthcare payers and Accountable Care Organizations.

Analytics platform for crowdfunding investors

Revenue guidance platform for B2B marketing, sales, and customer-success teams.

AI-powered relationship marketing platform for SMBs

Immersive VR training for healthcare professionals

Mobile-first field sales CRM with route optimization

Enterprise imaging interoperability platform for clinical records and imaging exchange

Subscription dining membership that subsidizes members when they dine in at local restaurants.

Non-destructive testing platform connecting inspection teams with experts, AI tools, and secure digital workflows.

AI workspace for technical sales teams managing complex B2B sales and post-sales handoffs.

Product analytics and user guidance platform

People analytics / HR tech platform

Solid-state electronics for refrigeration without harmful gases

Carbon-negative building materials from fast-growing grass

AI clinical intelligence connecting fragmented health data

AI enterprise knowledge management and assistant platform

Healthcare data analytics platform for physician practices, hospitals, and healthcare organizations.

Agentic commerce optimization software and consulting platform for brands and retailers preparing product catalogs for AI shopping agents.

Sales organization ratings and review platform

Location-based audience analytics

AI-native legislative intelligence platform; parses state legislative input, generates contextual summaries, and delivers tailored impact analysis to lobbyists, advocates, policy teams, legal entities, and government affairs professionals.

AI platform transforming local marketing through authentic customer-generated content

Proprietary cameras to auto-recognize returning drive-thru customers for loyalty programs

Multilingual shipping platform with joint headquarters in Cary and Medellin.

AI-powered media intelligence and monitoring

Community clinical-trials organization connecting physicians and patients to research opportunities.

On-demand mobile car care for consumers and fleets

Date-sweetened chocolate brand.

Virtual notepad for professional software developers

Utility-scale solar development

Solar energy accessibility platform

Clinical smart-toilet system for automated urine-output monitoring.

Universal instrument tracking technology for real-time virtual live fluoroscopy.

Interactive expedition and guest-engagement platform for parks, zoos, museums, and other venues.

AI platform for go-to-market messaging performance optimization.

AI platform for community pharmacy clinical services.

AI tools for private-equity deal origination and business development.

Healthcare software that generates personalized care plans for cognitive decline, depression, and related conditions.

Contact-level advertising platform for reaching identified B2B buyers.

AI middleware marketplace connecting healthcare systems with vetted AI tools

AI-powered real-time coaching during sales calls

AI marketing compliance platform for regulated industries. Reviews creative approvals, employee social posts, and marketing campaigns for brand, legal, and regulatory compliance across 50 states. Customers include insurance carriers, credit unions, telehealth companies, and fintech teams. Backed by Techstars. Founded 2024 in Durham by Austin Melonie Carroll, former financial-product marketing lead at Brex, Mercury, and Capital One.

Evidence-based confidential adolescent healthcare platform for physical and mental health

AI-powered health engagement platform

Durham deep-tech building autonomous tethered drones (teUAV) for airborne power generation and persistent ISR, sensing, communications, and electronic-warfare missions, primarily for U.S. defense customers.